莱娜在父亲的阴影下每天过著地狱般的生活,她唯一来往的对象是旅馆同事穆法塔斯,莱娜从未答应但也没拒绝他的追求,痛苦的莱娜只想挣脱生活中的恶性循环;在城市的另一端,有位技师正为他刚过世的妻子哀伤,一只装有他妻子衣物的行李箱,竟出其不意地改变莱娜的命运… Because of her father's inappropriate behavior, Zeynep, a hotel housekeeper, spends hellish nights. The only person with whom she has a relationship is Mustafa, a young man who works in the same hotel and who is interested in Zeynep. Zeynep is trying to escape from the vicious circle in which she finds herself. In another part of the city, Selcuk, a sound technician, is struggling with the guilt he feels over the recent death of his wife. The suitcase that contains Selcuk's wife's clothes will change Zeynep's fate in a most unexpected manner.
玛丽(凯特·哈德森 Kate Hudson 饰)是个开朗上进的大龄女青年,虽然年轻,但在公司很受高层器重,事业蒸蒸日上,虽然单身,但有许多好朋友,非常享受生活。但是不幸依旧降下,她被诊断患了癌症,更不可思议的是,伴随着厄运降临的还有爱情,她和主治医师、腼腆的西班牙裔小伙儿朱利安(盖尔·加西亚·贝纳尔 Gael García Bernal 饰)产生了感觉。开朗的性格让她笑对病痛,但难免会抑郁、绝望、诅咒命运的不公,一个又一个情绪期里面,对爱情的渴望和抗拒又同时存在。
死亡如约而至时,玛丽会选择以怎样的表情来面对……