因家庭的缘故,高中女生艾玛(索菲亚·布莱克-德埃利亚 Sofia Black-D'Elia 饰)随教授生物的父亲(迈克尔·凯利 Michael Kelly 饰)搬到了加州的影子峡谷居住。在此期间,一种可怕的蠕虫在全世界蔓延,许多国家受到摧残,而美国各州危机也相继呈现。某天课上,艾玛的好朋友突然发病暴走,学校被迫关闭。在此之后,疫情迅速蔓延。父亲前往机场迎接被困的母亲,艾玛则和姐姐史黛西(安娜丽·提普顿 Analeigh Tipton 饰)留守家中。没过多久,美国总统宣布对加州进行戒严,凡居住在疫区的百姓不准随便出入,而被感染者则时刻威胁着幸存者的生命。
Devi is gifted with Extra Sensory Perception (ESP). Her gift comes to light one day while playing tennis with her friend, Sudha, when she has a vision of her sister, Rama, being shot to death by a man in a black raincoat. She telephones Rama, finds she is safe and is relieved. Shortly thereafter Rama disappears, the police are notified, but are unable to find any trace of her. Devi then meets multi-millionaire, Ram Kumar, both fall in love and get married. She moves into his once abandoned and legally disputed bungalow, and that's when she starts having visions again. These visions lead her to a wall that is loosely plastered. She breaks down the wall with a pick-axe and finds a skeleton of a woman, who is later identified as Rama. Now having come to know that her premonitions are more or less accurate, Devi starts to have another vision - this time of a woman being stabbed by a bald man...